Moohi Yoo Selected Research

4- (3- amino- 4- (2,4,5- trifluorophenyl)butanoyl)- 3- (tert- butoxymethyl)piperazin- 2- one

6/2011

Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.

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Moohi Yoo Research Topics

Disease

5	Inflammation (Inflammations) 02/2010 - 12/2005
3	Erectile Dysfunction 07/2010 - 03/2005
3	Dry Eye Syndromes (Dry Eye Syndrome) 02/2010 - 01/2009
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2007 - 01/2006
3	Asthma (Bronchial Asthma) 06/2006 - 12/2005
2	Fibrosis (Cirrhosis) 07/2010 - 01/2009
2	Respiratory Hypersensitivity 06/2006 - 12/2005
2	Obesity 05/2006 - 01/2004
2	Body Weight (Weight, Body) 05/2006 - 01/2004
2	Dehydration (Water Stress) 04/2006 - 01/2006
1	Type 2 Diabetes Mellitus (MODY) 06/2011
1	Prostatic Neoplasms (Prostate Cancer) 07/2010
1	Hypoxia (Hypoxemia) 07/2010
1	Hypertension (High Blood Pressure) 03/2009
1	Portal Hypertension 01/2009
1	Corneal Injuries 01/2009
1	Stomach Ulcer (Gastric Ulcer) 05/2008
1	Gastritis 05/2008
1	Ulcer 11/2007
1	Hyperplasia 10/2007
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 10/2007
1	Hypercholesterolemia 01/2007
1	Stomach Neoplasms (Stomach Cancer) 01/2007
1	Eosinophilia 06/2006
1	Pneumonia (Pneumonitis) 04/2006
1	Airway Remodeling 04/2006
1	Infections 06/2005
1	Ganglion Cysts (Ganglion) 03/2005

Drug/Important Bio-Agent (IBA)

7	udenafilIBA 07/2010 - 03/2005
7	recoflavoneIBA 02/2010 - 03/2006
4	Phosphodiesterase 5 InhibitorsIBA 07/2010 - 01/2007
4	CytokinesIBA 02/2010 - 12/2005
3	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2009 - 01/2007
3	Immunoglobulin E (IgE)IBA 06/2006 - 12/2005
3	DA-9201IBA 06/2006 - 12/2005
2	flavoneIBA 02/2010 - 01/2006
2	MucinsIBA 06/2009 - 01/2009
2	Pharmaceutical PreparationsIBA 06/2009 - 04/2006
2	FlavonoidsIBA 05/2008 - 01/2006
2	NF-kappa B (NF-kB)IBA 01/2007 - 12/2005
2	OvalbuminIBA 06/2006 - 12/2005
2	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 06/2006 - 12/2005
2	Glucose (Dextrose)FDA LinkGeneric 05/2006 - 01/2004
2	DA-7867IBA 04/2006 - 06/2005
1	4- (3- amino- 4- (2,4,5- trifluorophenyl)butanoyl)- 3- (tert- butoxymethyl)piperazin- 2- oneIBA 06/2011
1	AmidesIBA 06/2011
1	Endothelin B ReceptorIBA 07/2010
1	salicylhydroxamic acid (SHAM)IBA 07/2010
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 07/2010
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 07/2010
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 07/2010
1	Therapeutic UsesIBA 02/2010
1	Atropine FDA LinkGeneric 06/2009
1	Scopolamine (Hyoscine)FDA Link 06/2009
1	Losartan (Cozaar)FDA LinkGeneric 03/2009
1	Amlodipine (Norvasc)FDA LinkGeneric 03/2009
1	SuspensionsIBA 01/2009
1	TabletsIBA 05/2008
1	Acetic Acid (Vinegar)FDA LinkGeneric 11/2007
1	Complementary DNA (cDNA)IBA 01/2007
1	PlatinumIBA 01/2007
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2007
1	Dexamethasone (Maxidex)FDA LinkGeneric 06/2006
1	CholesterolIBA 05/2006
1	Triglycerides (Triacylglycerol)IBA 05/2006
1	Blood Proteins (Serum Proteins)IBA 04/2006
1	Messenger RNA (mRNA)IBA 01/2006
1	Interleukin-4 (Interleukin 4)IBA 12/2005
1	Interleukin-13IBA 12/2005
1	ChemokinesIBA 12/2005
1	Cell Adhesion MoleculesIBA 12/2005
1	Interleukin-5 (Interleukin 5)IBA 12/2005
1	Linezolid (Zyvox)FDA Link 06/2005
1	Streptozocin (Streptozotocin)FDA Link 03/2005
1	Sucrose (Saccharose)IBA 01/2004
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2004
1	4-aminomethyl-1,2-naphthoquinoneIBA 01/2004

Therapy/Procedure

5	Oral Administration 11/2007 - 03/2005
2	Intravenous Administration 04/2006 - 01/2006
1	Prostatectomy (Retropubic Prostatectomy) 07/2010
1	Ligation 01/2009